Research Identifies Potential Predictors of Vascular Cognitive Impairment

Posted: 11/7/2018
Research at the University of Kentucky Sanders-Brown Center on Aging has identified two potential ways to predict vascular cognitive impairment and dementia (VCID) – the second leading cause of dementia behind Alzheimer's disease.VCID results from injuries to the vessels that supply blood to the brain, including mini-strokes, and/or by risk factors that are also known to cause heart disease or stroke:  high cholesterol, smoking, high blood pressure and/or diabetes. About 10 percent of all dementia cases are caused by VCID, while Alzheimer's accounts for between 60 and 80 percent. Sometimes Alzheimer's and VCID can occur simultaneously, which is... FULL STORY
Tags: UK Sanders-Brown Center on Aging, Research

New Grant Provides Retinopathy Screenings for Diabetics

Posted: 10/24/2018
Diabetes is a complex condition that requires patients to check in with providers across a number of specialties. Multiple appointments with practitioners can mean endless rounds of scheduling, traveling and follow-ups. Many patients don't have the flexibility to take off work, the means to travel, or access to education materials to help them manage their condition. But thanks to a new grant secured by UK HealthCare's CE Central and their partners at DKBmed, vital screenings for diabetic retinopathy will be conducted by the patient's primary care provider.Starting in March 2019, diabetic patients can receive retinopathy screenings at their primary care clinic.... FULL STORY
Tags: Ophthalmology, Research

UK Research Links Signaling Pathways to Combatting Fetal Alcohol Syndrome

Posted: 10/19/2018
Fetal alcohol spectrum disorders are an array of conditions that can occur in a person whose mother consumed alcohol during pregnancy. Fetal alcohol syndrome (FAS), the most severe of these conditions, often results in physical abnormalities, behavioral development issues and intellectual disabilities.  Researchers at the University of Kentucky College of Medicine have discovered that targeting a specific signaling pathway could potentially provide a new therapeutic avenue for treating FAS. Kai Zhang, a doctoral student in the Department of Pharmacology and Nutritional Sciences, has worked as a member of  Professor Jia Luo’s... FULL STORY
Tags: Research, Pharmacology and Nutritional Sciences


Posted: 10/18/2018
The NIH Center of Biomedical Research Excellence (COBRE) on Obesity and Cardiovascular Diseases, in collaboration with the Center for Clinical and Translational Sciences (CCTS) announce the availability of limited funds to support pilot projects focused on research examining obesity-associated diseases. Emphasis for support will be placed on pilot projects that examine the relationship between obesity and cardiovascular diseases, type 2 diabetes, cancer, and neurodegenerative diseases.  These pilot grants are intended to assist investigators new to this area of research to generate sufficient data to be competitive for extramural funding.Funding Amount:Individual... FULL STORY
Tags: Research, Grants and Funding, cardiovascular disease

Register for Markesbery Symposium's Scientific, Community Sessions

Posted: 10/4/2018
Alzheimer's disease wreaks emotional havoc on patients, who are robbed of their memories, their dignity and their lives. It’s financially devastating as well: care for Alzheimer's patients is predicted to top $1 trillion by about the time children born today are having children of their own.Almost six million Americans are living with Alzheimer's disease, which likely means that all of us know someone whose lives have been touched — directly or indirectly — by dementia. And since that number is expected to rise to nearly 14 million by 2050, Alzheimer's will likely hit closer to home for many of us. The UK Sanders-Brown Center on Aging, a world leader in... FULL STORY
Tags: UK Sanders-Brown Center on Aging, Alzheimer's research, Research

Two Sanders-Brown Studies Show Connection Between Diet, Cognitive Function

Posted: 10/2/2018
We've all experienced a "gut feeling" — when we know deep down inside that something is true. That phenomenon and others, aptly describe what scientists have now demonstrated: that the gut and the brain are more closely connected than we once thought, and in fact the health of one can affect the other.Capitalizing on this relatively new scientific concept, Ai-Ling Lin, and her colleagues at the University of Kentucky Sanders-Brown Center on Aging, have published two studies that demonstrate the effect of diet on cognitive health in animals.The first, in Scientific Reports, demonstrated that neurovascular function improved in mice who followed a... FULL STORY
Tags: UK Sanders-Brown Center on Aging, Research, Alzheimer's disease

Cardiovascular Research Day Features Science From Regional, National

Posted: 9/26/2018
Last week, more than 200 faculty, staff, and trainees from across the nation attended the Gill Heart & Vascular Institute's Cardiovascular Research Day to share the latest research on cardiovascular health. The event, in its 21st year, showcased the research of postdoctoral fellows, students, and faculty, much of it focused on the prevention or reversal of cardiovascular diseases, including heart attacks and strokes. This year’s event featured two judged poster sessions; four trainee presentations; a research blitz of one-minute research presentations and faculty oral presentations from distinguished alumni Gregory Graf, PhD, Professor in the University of... FULL STORY
Tags: Saha Awards, Research

Research Facility Shows What Kentucky Can Do

Posted: 9/21/2018
A research facility expressly devoted to addressing and eradicating the state’s most significant health disparities was opened Friday morning by the University of Kentucky Board of Trustees and President Eli Capilouto, and many of the Commonwealth’s leading policymakers.“Today, joined by our partners in progress, we open the doors to a modern facility that will be a shining beacon of hope — a testament to the idea that we can turn the tide on disease and suffering in the Commonwealth,” Capilouto said. “UK’s new multidisciplinary research building is the result of a $265 million partnership between the state and its flagship university, equally committed to a better and... FULL STORY
Tags: Research

Markey Earns Renewal of Prestigious 5-Year National Cancer Institute

Posted: 8/10/2018
The University of Kentucky Markey Cancer Center announced Friday that the National Cancer Institute (NCI) renewed its national cancer center designation for the next five years. The UK Markey Cancer Center remains one of only 70 NCI-designated centers in the country and the only one in Kentucky.“UK was founded for the people of Kentucky, and still today, they turn to us. Five years ago, we stood together and declared cancer in Kentucky had a new foe. That is a promise we intend to keep, and we are proud to announce further investment in that promise with the renewal of the Markey Cancer Center’s NCI-designation,” said UK President Eli Capilouto. “The... FULL STORY
Tags: Markey Cancer Center, Research

UK Doctoral Candidate Selected to Participate in New Advocacy Program

Posted: 7/21/2018
Ten researchers from institutions across the U.S. have been selected to participate in the American Society for Biochemistry and Molecular Biology (ASBMB) Advocacy Training Program, a rigorous six-month program aiming to produce the next generation of science advocates. Among those chosen is Aria Byrd, a doctoral candidate in the University of Kentucky College of Medicine and researcher in the Fillmore Brainson Lab. "I've constantly been in environments that have motivated me to refine my passions and find my niche in the science world," said Byrd, "As I've matured, the significance of science communication has become... FULL STORY
Tags: Biochemistry, Research

New Clinical Trial Takes Personalized Approach for Rare Type of ALS in

Posted: 6/13/2018
ALS, or amyotrophic lateral sclerosis, is a neurodegenerative disease of some fame in the United States. Many Americans know the illness, which currently has no cure, as Lou Gehrig’s disease, after the beloved baseball player whose career and life were cut short by the condition in the 1930s and 40s. More recently, renowned physicist Stephen Hawking died of ALS. Perhaps more than anyone else, Hawking reminds us of the particular cruelty of the disease, which slowly robs a person of muscle movement while leaving their cognitive abilities intact. The average life expectancy after diagnosis is only four to five years and nearly everyone with ALS ultimately dies from the... FULL STORY
Tags: Research, ALS

Undergraduate Research Mentor Award Winners Announced

Posted: 6/13/2018
 Luke Bradley, Janice Fernheimer and Gregory Luhan received the University of Kentucky 2018 Excellent Undergraduate Research Mentor Award. This student-nominated award recognizes UK faculty members who demonstrate an outstanding commitment to mentoring undergraduate researchers, providing exceptional undergraduate research experiences, as well as supporting and promoting the undergraduate research initiatives on campus.Eighteen faculty mentors were nominated for the award by their students.Bradley is an associate professor and research mentor in the Department of Neuroscienceand the Department of Molecular and Cellular... FULL STORY
Tags: Research