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Saha Cardiovascular Research Center Opens Application Process for 2015 Saha Awards

Posted: 2/26/2015

The 2015 Saha Awards application process is now open.

These awards are given to encourage and support staff and students with an interest in and dedication to cardiovascular medicine. Each award includes an unrestricted $1000 prize, a certificate and recognition at the University of Kentucky Gill Heart Institute Cardiovascular Research Day held on October 2, 2015 at the Lexington Convention Center.

Award Categories

·  MD, PhD Student Award - The eligible student must be currently participating in the MD, PhD program at the University of Kentucky and show an active interest in cardiovascular medicine.    2015 Saha Awards Announcement | Saha Awards Student Application

·  Medical Student Award - Students must be currently enrolled in the University of Kentucky College of Medicine and must demonstrate an interest in cardiovascular medicine.      2015 Saha Awards Announcement | Saha Awards Student Application

·  University of Kentucky Nursing Student Award - The eligible student must be enrolled in the University of Kentucky Nursing... FULL STORY

 

UK Researchers Awarded Grant to Study Aggressive Cancer Metastasis

Posted: 2/25/2015
The National Cancer Institute recently awarded a two-year, $357,743 grant to University of Kentucky Markey Cancer Center researchers to study the role of a certain protein in aggressive cancer metastasis. The lab of Kathleen O'Connor, professor in UK's Department of Molecular and Cellular Biochemistry, studies how tumor cells interact with their environment to make cancer more aggressive. Specifically... FULL STORY
Tags: Markey Cancer Center, Grants and Funding
 

UK Proposal Development Office to Offer Workshops on New NIH

Posted: 2/24/2015
The Proposal Development Office (PDO) at UK has scheduled workshops to assist faculty in meeting the requirements for the new NIH Biosketch formats.  NIH will require this new format for all submissions received on or after May 25, 2015.   “Preparing Your New NIH Biosketch”March 26, 201512:00-1:00 pmNiles Gallery, Lucille Little Fine Arts LibraryClick here to register.April 8, 201512:00-1:00 pm415... FULL STORY
 

Registration Now Available for UK Barnstable Brown Obesity & Diabetes

Posted: 2/2/2015 - Tags: Research, Barnstable Brown Obesity and Diabetes Research Day
Registration is now available for the fifth annual Barnstable Brown Obesity... FULL STORY

UK Sanders-Brown Researcher Receives NIH Grant Totaling $1.1 Million

Posted: 1/28/2015 - Tags: UK Sanders-Brown Center on Aging, Research, Grants and Funding
Dr. Gregory J. Bix of the University of Kentucky Sanders-Brown Center on Aging, has been awarded a $1.1 million grant from the National Institutes of Health to study a promising treatment for ischemic stroke. The five-year grant expands Bix's earlier research on a protein called Perlecan Domain V, which appears to foster healing after strokes caused by blood clots in the brain. "Perlecan seems to promote neurorepair in endothelial cells by blocking a receptor called A5B1 Integrin," Bix said. "In fact, genetically engineered mice that are completely deficient in the A5B1 receptor in endothelial cells show amazingly little to no injury after a stroke." "It's... FULL STORY

UK Researchers Solve Metabolic Mystery Lending Insight Into Lafora Disease

Posted: 1/26/2015 - Tags: Biochemistry, Research
Scientists at the University of Kentucky College of Medicine have determined how an enzyme essential for energy metabolism functions, solving a mystery eluding molecular biologists for decades. Matthew Gentry, Ph.D, and Craig Vander Kooi, Ph.D, associate professors of molecular and cellular biochemistry, and researcher Madushi Raththagala, Ph.D, recently discovered the role of the enzyme laforin in modifying human glycogen and thereby preventing neurodegeneration. Their work provides fundamental insights that link energy metabolism with the fatal, neurodegenerative form of epilepsy called Lafora disease. These findings were reported Jan. 22, 2015, in the journal,... FULL STORY

UK Study Finds Potential New Drug Target for Lung Cancer

Posted: 1/23/2015 - Tags: Lung Cancer, Markey Cancer Center, Research
A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a key enzyme and its associated metabolic programming may lead to novel drug development to treat lung cancer. Cancer cells undergo metabolic alterations to meet the increased energy demands that support their excess growth and survival. The Krebs cycle in the mitochondria of cells is used to supply both energy and building materials for cell growth. Two mitochondrial enzymes – pyruvate carboxylase (PC) and glutaminase replenish carbon to the Krebs cycle.   Published in the Journal of Clinical Investigation, the study collected metabolic data directly from more than... FULL STORY

UK Study Disputes Previous Theories on Loss of Muscle Stem Cells and Aging

Posted: 1/7/2015 - Tags: Center for Muscle Biology, CCTS, Research
Professional athletes often spend hours in a gym working to build strong healthy muscles needed to keep them at the top of their game. But strong muscles help all humans maintain peak physical performance – the non-athlete, the young and the old – and can prevent frailty later in life, a condition that can exacerbate an illness and even shorten one's life. According to Charlotte Peterson, co-director of the Center for Muscle Biology at the University of Kentucky, "muscle powers health." Peterson, who is also a professor and associate dean for research in the College of Health Sciences and associate director of the UK Center for Clinical and Translation Sciences (CCTS... FULL STORY

UK Researchers Point to Impact of Combined Brain Injury and PTSD in War

Posted: 12/22/2014 - Tags: Research, Rehabilitation Medicine
The U.S. Department of Defense identifies mild traumatic brain injury, or mTBI, as one of the signature injuries impacting veterans who served in Iraq and Afghanistan. Often associated with the blast of an improvised explosive device (IED) in the field, an mTBI is commonly diagnosed in concurrence with posttraumatic stress disorder, a separate condition triggered by the traumatic event. A recent study suggests that 12 to 16 percent of all veterans involved in the Iraqi conflict have a history of mTBI and an estimated 13 to 17 percent of veterans return with a diagnosis of PTSD resulting from an injury. One-third of all veterans with a TBI also suffer from PTSD.... FULL STORY

94 Year-Old Lexington Woman Gives Back as Research Volunteer

Posted: 12/19/2014 - Tags: Research, UK Sanders-Brown Center on Aging, Clinical Trials
On Dec. 2, a very special group of people gathered to celebrate a very special gift. "Participation in clinical trials is a truly noble act, and we consider the people who volunteer for research part of our family," says Dr. Gregory Jicha, a professor at the University of Kentucky's Sanders-Brown Center on Aging. "So it's natural that we would gather at the holidays to share a little joy and thanksgiving." Every year, the Sanders-Brown Center on Aging has a party for patients who have volunteered to participate in research at the center. It's an annual highlight for patients and staff alike, who often form special bonds over the course of several years.... FULL STORY

'UK at the Half' Reports on $7 Million Grant to Fight Lung Cancer

Posted: 12/8/2014 - Tags: Behavioral Science, Lung Cancer, Research
University of Kentucky College of Medicine faculty member in behavioral science and Director of the Kentucky LEADS Collaborative Dr. Jamie Studts was featured during the "UK at the Half" that aired during the UK vs. Providence College basketball game, broadcast on the radio Nov. 30. The Kentucky LEADS Collaborative received a three-year, $7 million grant from the Bristol-Myers Squibb Foundation's Bridging Cancer Care Initiative. Kentucky has more cases of lung cancer than any other state and its lung cancer mortality rate is 50 percent higher than the national average. The collaborative includes the UK Markey Cancer Center, The University of Louisville's James Graham... FULL STORY

UK Physiologist Leads Team that Identifies Receptors Activated by Odors

Posted: 11/26/2014 - Tags: Research, Physiology
A group of physiologists led by University of Kentucky’s Tim McClintock have identified the receptors activated by two odors using a new method that tracks responses to smells in live mice. Their research was published in the latest edition of The Journal of Neuroscience. Using a fluorescent protein to mark nerve cells activated by odors, McClintock and his colleagues identified receptors that allow mouse nerve cells to respond to two odors: eugenol, which is a component of several spices, most notably cloves, and muscone, known as musk. "This new method could help us understand how these receptors allow mice, and eventually humans, to detect and... FULL STORY

Markesbery Symposium Presents Latest Research on Aging and Dementia

Posted: 11/25/2014 - Tags: UK Sanders-Brown Center on Aging, Alzheimer's research, Research
More than 450 scientists, researchers and laypeople converged on Lexington last week for the fourth annual Markesbery Symposium on Aging and Dementia, hosted by the University of Kentucky's Sanders-Brown Center on Aging. The two-day program offered sessions for both scientific and community audiences to share current findings, trends and the latest updates on dementia and aging disorders, particularly Alzheimer's disease. The scientific session and poster presentations were held on Friday, Nov. 21, at the UK Albert B. Chandler Hospital. This session featured speakers William E. Van Nostrand, Ph.D., of Stony Brook University, and Dr. Steven M. Greenberg of... FULL STORY

'Three Minute Thesis' Prepares Students to Present Research

Posted: 11/21/2014 - Tags: Research
Four students seeking their master's degrees and five students doctoral programs competed last week in an event designed to prepare them for presenting research. The "Three Minute Thesis" event, hosted by the UK Graduate School and the Graduate Student Congress, is a research communication initiative requiring graduate students to speak succinctly and engagingly about their current research to a nonspecialist audience. It provides students with the opportunity to practice presenting their work, and to receive feedback from a panel of judges. A preliminary competition took place during the previous week, culminating with a final competition Tuesday, Nov. 11.... FULL STORY

HIV/AIDS Drugs Could Be Repurposed to Treat Age-Related Macular

Posted: 11/20/2014 - Tags: Ophthalmology, Ophthalmology and Visual Sciences, Research
A landmark study published today in the journal Science by an international group of scientists, led by the laboratory of Dr. Jayakrishna Ambati, professor and vice chair of the Department of Ophthalmology... FULL STORY