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Center for Molecular Medicine Sponsors Three Scientific Cores

Posted: 7/22/2014

The University of Kentucky Center for Molecular Medicine sponsors three scientific cores for use by researchers at the University of Kentucky.  These include a Protein core providing services for the production and characterization of proteins, an Organic Synthesis core synthesizing small molecules not commercially available, and a Genetic Technologies core producing recombinant virus and other molecular biological reagents.  These cores, sponsored in part by a Center of Biological Research Excellence grant, through the National Institute of General Medicine, provide low cost services to facilitate the research of its users.  For University of Kentucky faculty the core service charges are further reduced through supplementation.  In addition investigators without or with limited research funding can apply for vouchers, which, if approved will cover the cost of the services provided.  For further information visit the COBRE website at: or contact Lou Hersh at:


PDO Sends Funding Alert Emails

Posted: 7/22/2014
Do you receive funding alerts from the University’s Proposal Development Office?  You can subscribe to receive these email notices based on your area(s) of research interest.  A subscription form is found by clicking here.   

NIH Reformatting Funding Opportunity Announcements

Posted: 7/22/2014
[From the July 17 NIH “eSubmission Items of Interest”] You may have noticed that newer NIH funding opportunity announcements (FOAs) have a different look. Some aspects of the old format (e.g., table structure) did not allow for easy page resizing across electronic devices and had to be reworked. You should now find it easier to view FOAs on various screen sizes of phones, tablets, laptops, desktops... FULL STORY

Alzheimer's With Cerebrovascular Disease Compounds Cognitive Decline

Posted: 7/8/2014 - Tags: UK Sanders-Brown Center on Aging, Research
Researchers from the Sanders-Brown Center on Aging at the University of Kentucky have been able to confirm anecdotal information on patients with both Alzheimer's disease (AD) and cerebrovascular disease (CVD) using mouse models in two different studies. The findings of these two studies, which were recently published in Acta Neuropathologica and Alzheimer's Research... FULL STORY

Guo Lab Reports Finding of Revolution Biomotors in Many Bacteria and

Posted: 6/30/2014 - Tags: Research, Biomedical
Scientists at the University of Kentucky, led by nano-biotechnologist Peixuan Guo, have made some critical discoveries over the past year into the operation of biomotors, the molecular machines used by viruses and bacteria in the packaging of DNA. Biomotors function similarly to mechanical motors but on a nano-scale. Last year, Guo's team reported the discovery of a new, third class of biomotor, unique in that it uses a "revolution without rotation" mechanism. Rotation is the turning of an object around its own axle, as the Earth does every 24 hours. Revolution is the turning of an object around a second object, as the Earth does around the sun. Recently, Guo's... FULL STORY

UK-TLC Partnership Nurtures Promising Young Science Students

Posted: 6/25/2014 - Tags: Biomedical, Research, TLC
Not all learning experiences are created equally – and at the Learning Center at Linlee, an innovative partnership with the University of Kentucky College of Medicine allows young students to get rich, hands-on experience in the sciences and better their chances of succeeding in college and beyond. As part of the Fayette County Public School System, The Learning Center (TLC) is an alternative school for at-risk students who are facing personal challenges that might impede their ability to learn. These include socioeconomic factors, and, perhaps surprisingly, intellectual giftedness. Students may struggle inside a traditional classroom because the learning style or... FULL STORY

UK, Norton Expand Research and Educational Collaborations to Improve

Posted: 6/24/2014 - Tags: Research, Norton Healthcare
UK HealthCare and Norton Healthcare are building upon their history of collaboration to expand research and educational collaborations between the two institutions, with the goal of improving health and health care for all Kentuckians. Beginning July 1, educational and research initiatives between UK and Norton will be lead by Dr. Stephen Wyatt, who most recently served two successful terms as the founding dean of the University of Kentucky College of Public Health. Wyatt will return to the UK College of Medicine, with joint appointment as vice president for research at Norton Healthcare. During Wyatt's tenure as dean, the College of Public Health experienced... FULL STORY

Sanders-Brown Center on Aging Selected for Major Clinical Trial

Posted: 6/19/2014 - Tags: UK Sanders-Brown Center on Aging, Research, Clinical Trials
The University of Kentucky's Sanders-Brown Center on Aging is participating in a landmark multi-center clinical trial of an experimental drug that has the potential to prevent Alzheimer's disease (AD). The A4 Study will recruit 1,000 participants ages 65-85 to test an amyloid antibody that may prevent memory loss caused by Alzheimer's disease. Amyloid is a protein normally produced in the brain that can build up in older people, forming plaque deposits in the brain. Scientists believe this buildup of deposits may play a key role in the eventual development of Alzheimer's. Sanders-Brown is the only center in Kentucky and the only center within 200 miles of... FULL STORY

Cardiovascular Science Program Receives $1.2 Million

Posted: 6/18/2014 - Tags: Research, Gill Heart Institute, Grants and Funding
The National Institutes of Health has renewed a 5-year, $1.2 million grant to the University of Kentucky to help prepare clinical scholars for leadership positions in cardiovascular research. The UK Training Program for Clinical Scholars in Cardiovascular Science prepares clinical and postdoctoral fellows in medicine, nursing and pharmacy to assume leadership positions directing multidisciplinary research in the field of cardiovascular medicine. "The University of Kentucky has invested substantial resources to develop a highly collaborative training environment that leverages our strengths in cardiovascular science," said Dr. Leigh Ann Callahan, program co-... FULL STORY

UK Researchers Decode Activity of Starch Modifying Enzyme to Provide

Posted: 6/12/2014 - Tags: Research
Scientists at the University of Kentucky College of Medicine have gained a new understanding of an enzyme essential for breaking down plant starch, a process used in agriculture, manufacturing and biotechnology. Dr. Matthew Gentry and Dr. Craig Vander Kooi, associate professors of molecular and cellular biochemistry at the University of Kentucky, and graduate student David Meekins, have decoded the natural process plants use to break down starch. Their discovery will lead to more environmentally friendly and cost-efficient methods of processing starch, with significant applications for agriculture and biotechnology. Their findings were reported May 20 in the... FULL STORY

Advanced MRI Allows Researchers to Visualize Early Indicators of Heart

Posted: 6/10/2014 - Tags: Pediatrics, Research, obesity
Children who suffer from obesity carry a burden of premature death into adulthood. Obese children have more than double the risk of mortality in their 30s and 40s compared to children who begin life with a healthy body mass index (BMI). In addition to being more likely to remain obese as adults, obese children are at a higher risk of developing a number of health conditions, including stroke, diabetes, depression, cardiovascular disease and certain types of cancer. Today, 30 percent of American children are overweight, 20 percent are considered obese and 5 percent are considered morbidly obese. Kentucky has one of the nation's highest rates of obesity. Because... FULL STORY

Wright Receives Retinal Research Foundation Award

Posted: 6/6/2014 - Tags: Ophthalmology, Research
Charles Wright, postdoctoral Fellow in the Department of Ophthalmology and Visual Sciences at the University of Kentucky College of Medicine, has received The Loris and David Rich Postdoctoral Scholar Award from the International Retina Research Foundation (IRRF). The Loris and David Rich Postdoctoral Scholar Award is one of three IRRF Scholar Awards that have been designated in honor of individuals who played a critical role in the development of the International Retinal Research Foundation and are meant to serve as a memorial to their efforts. Additionally, the awards were established to provide salary and research support in the amount of $35,000 per year for a... FULL STORY

Lung Cancer Patients May Benefit from Innovative Informatics Project

Posted: 5/30/2014 - Tags: Center for Clinical and Translational Science, Markey Cancer Center, Research, cancer
A multidisciplinary team of doctors, researchers, and informaticists the University of Kentucky is working to improve identification of lung cancer patients who are eligible to participate in clinical trials for novel treatments. Clinical trials are critical for advancing research into new and better treatments for patients, and the need for improved treatment of lung cancer is dire: Lung cancer is the leading cause of cancer death worldwide. Its burden is especially significant in the Commonwealth, where rates of lung cancer incidence and mortality are the highest in the country. In Appalachian Kentucky, the situation is even worse, with incidence rates nearly twice... FULL STORY

Annual Markey Research Day Showcases Cancer Research

Posted: 5/23/2014 - Tags: Markey Cancer Center, Research
The future looks bright for cancer research in Kentucky – on May 22, the University of Kentucky Markey Cancer Center held its annual Markey Cancer Center Research Day, highlighting the work of UK students, postdoctoral fellows and faculty from the past year. As the cancer center has grown, Markey’s research programs have become even more robust, helping propel the center into becoming the state’s first and only National Cancer Institute (NCI) designated cancer center. “The NCI is pretty much all about research – it’s a huge part of what they’re looking for when they award the designation,” said Markey Cancer Center Director Dr. Mark Evers. Research Day not... FULL STORY

UK Research Project to Focus on Lung Cancer, Pediatric Obesity in

Posted: 5/19/2014 - Tags: Center for Clinical and Translational Science, Appalachian Kentucky, Research, cancer
The University of Kentucky Center for Clinical and Translational Science (CCTS), in conjunction with the Appalachian Translational Research Network (ATRN), has awarded funding to two projects to develop sustainable, interdisciplinary, community engaged research in Appalachia. "Raising Awareness About Lung Cancer Screening: Kentucky Terminate Lung Cancer (TLC) Study," will partner with community-based organizations and focus groups to create an awareness campaign encouraging high risk individuals to obtain lung cancer screening. The second project, "Circadian Rhythm Parameters and Metabolic Syndrome Associated Factors in Young Children," will examine circadian rhythm... FULL STORY
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