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Clinical Trial Administration Support Project

Posted: 10/8/2015

At the Sr. ADR’s request, and with Dean de Beer’s approval, a decision was made in summer 2015 to engage the services of an outside consultant to guide the process of establishing an enterprise-level centralized support structure within the existing Sponsored Research Administrative Services (SRAS) office for administrative, financial, and regulatory activities related to clinical research activity – industry, government, and internally sponsored.

In August 2015, an RFP was distributed to group of consultants already having UKHC contracts in place to provide a range of health care-related financial consulting services.  Responses have been received and companies of interest are being scheduled to make in-person presentations during the month of October 2015.  A plan to make a decision and start work should be in place by January 1, 2016.   Watch the COM Research website for frequent updates on the process.    

Compliant Purchase Authorization on Grants

Posted: 10/8/2015
Certain fiscal responsibilities are entrusted to all employees of the University.    PIs agree to ensure acceptance of fiscal management responsibility of grants, via the certification statement on eIAFs that route prior to grant proposal submissions.      PIs may formally delegate purchasing authority for their grants to others, provided a formal... FULL STORY

The Center for Biomedical Research Excellence on Obesity and

Posted: 10/8/2015
The NIH Center of Biomedical Research Excellence (COBRE) on Obesity and Cardiovascular Diseases, in collaboration with the Center for Clinical and Translational Sciences (CCTS) announce the availability of limited funds to support pilot projects focused on research examining obesity-associated diseases (cardiovascular, diabetes, others). These... FULL STORY

UK's Butterfield Receives NIH Grant to Study Parkinson's Disease

Posted: 9/22/2015 - Tags: NIH Award, Research, UK Sanders-Brown Center on Aging
D. Allan Butterfield, professor in the University of Kentucky Department of Chemistry and Sanders-Brown Center on Aging (SBCoA), has been awarded a $413,000, two-year grant from the National Institutes of Health to study a new model of Parkinson's disease (PD). PD is the second most common age-related neurodegenerative disease in the United States and is manifested by movement abnormalities, postural instability, loss of smell (anosmia), deposition of the protein, alpha-synuclein, and in late stages, cognitive dysfunction. The brain is attacked by free radicals, many emanating from neuronal mitochondria (the powerhouse of the cell) to cause damage to proteins and... FULL STORY

Muscular Dystrophy Association Funds ALS Research at UK

Posted: 9/16/2015 - Tags: Research, Biochemistry, ALS
The Muscular Dystrophy Association (MDA) awarded Haining Zhu, a professor in the University of Kentucky Department of Molecular and Cellular Biochemistry, a three-year, $300,000 grant to study the underlying mechanisms of ALS. In an effort to accelerate treatments and cures for neuromuscular diseases, the MDA distributed $10 million in grants this summer to scientists conducting significant research on muscular dystrophy, ALS and other muscle-debilitating diseases. Zhu’s research seeks to understand the mutations of the Fused in Sarcoma (FUS) gene, which is a known cause of ALS. He was one of 36 international researchers — and the only researcher in Kentucky —... FULL STORY

American Heart Association Council Honors UK Cardiovascular Researcher

Posted: 9/10/2015 - Tags: research, American Heart Association
The American Heart Association’s Council on Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) will award Nancy Webb, a professor of pharmacology and nutritional sciences at the University of Kentucky, with its 2015 AHA Special Recognition Award in Arteriosclerosis. The ATVB council supports basic, translational and clinical research concerned with diseases of the blood vessels. The council annually bestows the Special Recognition Award to a member who has contributed significantly to the scientific council over time and enhanced this field of the profession. Arteriosclerosis, the leading cause of heart attack and stroke, occurs when plaque gradually... FULL STORY

UK Researchers Find “Dormant” Parasite Cysts Are Actually Quite Active

Posted: 9/8/2015 - Tags: research
A new University of Kentucky study in the journal mBio shows that tissue cysts of the parasite Toxoplasma gondii, long thought to be dormant, are quite active. Led by Anthony Sinai, professor at the UK College of Medicine, the study has significant implications on the understanding of chronic toxoplasmosis in the brain, a condition suggested to contribute to a range of neurological diseases including schizophrenia in humans, and the modulation of behavior in rodents. Toxoplasmosis can be acquired from the droppings of infected cats as well as the consumption of tissue cyst contaminated meat,infects roughly one-third of the human population. Infected individuals... FULL STORY

UK Researcher Awarded Grant to Study Link Between Obesity and Cancer

Posted: 8/13/2015 - Tags: Research, Obesity associated complications, National Cancer Institute
The National Cancer Institute (NCI) recently awarded a $750,000 grant to University of Kentucky researcher Fredrick Onono to study the potential link between obesity and breast cancer. Obese women are four times more likely to develop treatment-resistant breast cancer, but the exact mechanism for this observation is still largely a mystery. The link between high-fat diets and cancer development provides a clue that fats themselves may somehow be responsible for causing cells to malfunction. Onono, who recently became an assistant professor at the University of Kentucky, will work with fellow UK researchers Andrew Morris, Ashwini Anand Professor of Cardiology; Dr... FULL STORY