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Center for Clinical and Translational Launches New Website

Posted: 4/22/2014

The UK Center for Clinical and Translational Science (CCTS) has launched a new website that is especially oriented to researchers who currently use or could benefit from CCTS resources, including research services, funding opportunities, and education and career development.

The CCTS offers a spectrum of multidisciplinary support to assist investigators across the entire cycle of clinical and translational research, from protocol development and participant recruitment to regulatory affairs and evaluation. Researchers can easily navigate the new website to explore available resources and services and find contact information for further assistance.

The site lists open research funding announcements, and the “Services & Resources” tab offers a researcher-oriented listing of services by stage of research development. Investigators can also find information about CCTS core services (including biostatistics, informatics, clinical services, community engagement, drug and device development, and regulatory support) and electronic tools. The online CCTS Service Request Form facilitates access to these services and resources.

Additionally, the website includes information on the various educational and career development programs that CCTS offers for... FULL STORY

Tags: CCTS, Center for Clinical and Translational Science, Research

Guo Lab Shows Potential of RNA as Heat-resistant Polymer Material

Posted: 4/22/2014
A team of nanotechnology researchers at the University of Kentucky has discovered new methods to build heat resistant nanostructures and arrays using RNA. The research, led by Peixuan Guo, professor and William Farish Endowed Chair in Nanobiotechnology at the UK College of Pharmacy and Markey Cancer Center, is reported in an article titled "RNA as a Boiling-Resistant Anionic Polymer Material To... FULL STORY
Tags: Research, Markey Cancer Center

The University of Kentucky Aortic Program Announces the 2014

Posted: 4/21/2014
The University of Kentucky Aortic Program is proud to present the 2014 University of Kentucky Aortic Symposium on Thursday, September 4, - Saturday, September 6 in Lexington, KY. This event will provide a forum for the integration of basic science and clinical care discussions. It will feature talks on aortic aneurysmal diseases from leading experts, as well as abstracts in the form of oral and poster... FULL STORY

The Aging Brain and Fitness: How Are They Related?

Posted: 3/31/2014 - Tags: Research, Center for Clinical and Translational Science
We all know that exercise is good for us — it can help us lower blood pressure and cholesterol, maintain a healthy weight, and even improve mood and sleep. But can exercise improve the brain, especially as we age? A multidisciplinary group of University of Kentucky researchers is working to answer that question. Led by Nathan Johnson, an instructor in anatomy and neurobiology, and Dave Powell, an assistant professor in anatomy and neurobiology, the team includes Jody Clasey, professor of kinesiology and health promotion; Alison Bailey, assistant professor of cardiology; Brian Gold, associate professor of anatomy and neurobiology; and Doug Long, research analyst and... FULL STORY

Pilot Funding Program Supports Innovation, Community Engagement, and

Posted: 3/25/2014 - Tags: CCTS, Research
Translational research — the process of moving a laboratory discovery into clinical applications — is a long and complex process requiring diverse expertise, ranging from basic science and regulatory affairs to participant recruitment and rclinical application. According to the National Institutes of Health (NIH), it can take more than a decade for a lab discovery to result in a new treatment, medical device, or prevention method. Yet, despite extensive training for basic scientists and clinicians in their specific fields, few researchers have the training, experience, and resources to successfully initiate and complete the "bench to bedside" process of translational... FULL STORY

Kerur Receives Prestigious Award From National Eye Institute

Posted: 3/19/2014 - Tags: Ophthalmology and Visual Sciences, Research, Awards and Recognition
Nagaraj Kerur, a post-doctoral fellow in the lab of Dr. Jayakrishna Ambati, Department of Ophthalmology and Visual Sciences at the University of Kentucky College of Medicine, has received a prestigious K99/R00 award from the National Eye Institute (NEI). This Pathway to Independence award is one of only four given by the NEI in the nation annually. The award will provide up to five years of support consisting of two phases. The initial mentored phase will provide support for up to two years for the most promising and exceptionally talented new investigators. This initial phase of mentored support will enable Kerur to obtain additional training, complete research,... FULL STORY

Haynes is First to Identify Cellular Patterns of Contraction in Human

Posted: 3/19/2014 - Tags: Physiology, Center for Clinical and Translational Science, Research
When Premi Haynes was growing up in Pune, India, she attended Stella Maris High School, an English language convent school founded by Swiss nuns. Her second grade singing class used a book of English songs. One of the songs was "My Old Kentucky Home." At that time, Haynes had never heard of Kentucky, had no idea where it was, and had no particular ambition to go there. Some 20 years and a twist of fate later, today Haynes is defending her Ph.D. thesis in physiology at the University of Kentucky, where she's made a significant discovery about the cellular structure of the human heart, particularly related to heart failure. The findings have recently been published by... FULL STORY

Biobank Offers Way for Patients to Help Others

Posted: 3/6/2014 - Tags: Center for Clinical and Translational Science, CCTS, Research
In addition to providing high quality health care, the University of Kentucky is also committed to finding new treatments, tests, and cures for diseases. Now, patients at UK can contribute to that effort by agreeing to participate in the Research Registry and Specimen Bank, or the "biobank." When you have a medical procedure that involves, for example, drawing blood or sampling tissue, there is often material left over from the testing process that would otherwise be thrown away. By agreeing to participate in the biobank, you allow any "leftover" tissue from your normal medical procedures to be donated and stored in the biobank for medical research. Participation is... FULL STORY

UK Conference to Focus on Health Disparities in Appalachia

Posted: 3/6/2014 - Tags: CCTS, Research
Nearly 700 researchers, students, policymakers and community members will gather at the Lexington Convention Center March 27 to share research, mentor junior faculty, and enhance collaborations in clinical and translational science, with special focus on addressing health disparities in Appalachia. The 9th Annual Spring Conference and 4th Annual Appalachian Translational Research Network (ATRN) Summit will be hosted by the University of Kentucky Center for Clinical and Translational Science (CCTS). "This year’s theme will be health disparities, which fits well with CCTS efforts to boost research in many areas but with an eye to the needs of the people of Appalachia... FULL STORY

Markey Research Day Committee Now Accepting Abstracts

Posted: 3/6/2014 - Tags: Markey Cancer Center, Research
University of Kentucky faculty and students are invited to share their latest work in cancer research by submitting abstracts and attending Markey Cancer Center Research Day on May 22, 2014. For the fifth consecutive year, the Singletary Center for the Arts will play host to a daylong event that showcases the work of cancer researchers from all disciplines at the University of Kentucky. Last year, Markey Research Day featured 142 posters and more than 350 attendees. This year, Nobel Laureate Dr. Harold Varmus, director of the National Cancer Institute, will present the Susan B. Lester Memorial Lecture. As always, UK Markey Cancer Center Director Dr. Mark Evers... FULL STORY

Center for Clinical and Translational Science Calls for Mentor Award

Posted: 2/24/2014 - Tags: CCTS, Center for Clinical and Translational Science, Research, Awards and Recognition
At each annual spring conference, amidst keynote speakers and poster presentations, the University of Kentucky Center for Clinical and Translational Science (CCTS) presents a special class of awards--not for scientific discovery or novel research, but for mentorship. The Research Mentor Recognition Awards in Clinical and Translational Science honor UK faculty members who have committed their time and expertise to guide junior faculty, graduate students, post-doctoral fellows, research lab staff, or others to advance in their fields towards independent research. The deadline for nominations is Friday, February 28, and the awards will be presented at the 9th Annual... FULL STORY

UK College of Medicine Student Receives Fellowship Award

Posted: 2/17/2014 - Tags: Research, Alzheimer's research, UK Sanders-Brown Center on Aging
University of Kentucky College of Medicine student Melanie Pleiss has received the PhRMA Foundation Pre-Doctoral Fellowship in Pharmacology/Toxicology. The fellowship is a two year award that provides recipients with an annual stipend of $20,000 to support the research activities of a doctoral program. "The application process is extremely competitive, with just one applicant per institution allowed to apply and only a certain number of awards given to U.S. schools of medicine, pharmacy, dentistry or veterinary medicine," said Dr. Linda Van Eldik, director of the Sanders Brown Center on Aging at the University of Kentucky. "Melanie underwent an intense review and... FULL STORY

CROWD Lets You Give Back Through Participation in Clinical Research

Posted: 2/12/2014 - Tags: Center for Clinical and Translational Science, Research
Many Kentuckians join the crowds of fans at University of Kentucky athletic events. The UK Center for Clinical and Translational Science (CCTS) hopes that just as many people will "Be Part of the CROWD" - the Clinical Research Opportunities WildcatDatabase. CROWD is a secure and confidential tool that helps match people who are interested in participating in clinical research with current and potential future studies at the University of Kentucky. Across UK's campus, researchers are working towards new cures, treatments, and strategies to improve human health, especially for diseases that disproportionately affect Kentuckians. Of... FULL STORY

KL2 Program Creates Momentum for Junior Faculty and UK's Research

Posted: 2/11/2014 - Tags: Research, Center for Clinical and Translational Science, Mentored Program, Faculty
For junior faculty with clinical and/or teaching responsibilities, it's difficult to find enough time to prioritize their own research. On top of time constraints, junior faculty members often have limited experience in the precise art of writing successful federal grant applications and managing large grants. It takes time, training, and funding to accelerate a research career. The KL2 Career Development Program provides these resources to investigators to do just that. Operated by the University of Kentucky Center for Clinical and Translational Science (CCTS), the KL2 program is a competitive research training and funding opportunity for faculty looking to... FULL STORY

New UK Study Shows Potential for Targeting Aggressive Breast Cancers

Posted: 2/10/2014 - Tags: Markey Cancer Center, Research
A new study led by University of Kentucky Markey Cancer Center researcher Peter Zhou shows that targeting Twist, a nuclear protein that is an accelerant of the epithelial-mesenchymal transition (EMT) program in human cells, may provide an effective approach for treating triple-negative breast cancer. Triple-negative breast cancer has an activated EMT program, which is a process that provides cells with the increased plasticity (or flexibility) to adapt to stressed environments during embryonic development, wound healing, tissue fibrosis and metastasis. EMT provides tumor cells with stem cell-like characteristics, making them resistance to therapeutics and increasing... FULL STORY
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